The Neighborhood Uptown Uptown's hub of activity is located at the intersection of Hennepin and Lake just to the south of downtown. Though not exclusively gay, the dense and historic neighborhood near Lake Calhoun is a pleasant mix of many types. Here, find wonderful treats such as great Thai at Chiang Mai Tai, dessert at Caruso's Gelato Cafe and family-friendly fun at Bryant-Lake Bowling. There's plenty to do in Minneapolis.